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Cryptococcal peritonitis in a CAPD patient.

B Morris1, Y F Chan, J Reddy

  • 1Pathology Laboratory, Gisborne Hospital, New Zealand.

Journal of Medical and Veterinary Mycology : Bi-Monthly Publication of the International Society for Human and Animal Mycology
|January 1, 1992
PubMed
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Cryptococcus neoformans peritonitis occurred in a diabetic patient with end-stage renal disease on peritoneal dialysis. Intravenous fluconazole successfully cleared the fungal infection, suggesting it as a viable treatment option.

Area of Science:

  • Nephrology
  • Mycology
  • Infectious Diseases

Background:

  • Peritonitis is a serious complication for patients undergoing peritoneal dialysis.
  • Cryptococcus neoformans is an opportunistic fungal pathogen that can cause severe infections.

Observation:

  • A 50-year-old diabetic woman with end-stage renal disease on continuous ambulatory peritoneal dialysis developed asymptomatic peritonitis.
  • Infection was confirmed by the presence of Cryptococcus neoformans var. neoformans in peritoneal fluid.

Findings:

  • Intravenous fluconazole treatment led to the clearance of the fungal infection.
  • Delayed removal of the peritoneal dialysis catheter was performed after successful treatment.

Implications:

Related Experiment Videos

  • Fluconazole demonstrates potential as an effective therapeutic agent for cryptococcal peritonitis.
  • This case highlights the importance of considering fungal etiologies in dialysis-associated peritonitis, even in asymptomatic patients.