Related Experiment Video

Updated: Aug 16, 2026

Overcoming Unresponsiveness in Experimental Autoimmune Encephalomyelitis (EAE) Resistant Mouse Strains by Adoptive Transfer and Antigenic Challenge
08:38

Overcoming Unresponsiveness in Experimental Autoimmune Encephalomyelitis (EAE) Resistant Mouse Strains by Adoptive Transfer and Antigenic Challenge

Published on: April 9, 2012

IMMUNIZATION AGAINST RAUSCHER MOUSE LEUKEMIA WITH TISSUE CULTURE MATERIAL

G BARSKI, J K YOUN

    Science (New York, N.Y.)
    |August 13, 1965
    PubMed

    Long-term monolayer cultures of mouse thymus and spleen cells, chronically infected with Rauscher virus, showed only a very attenuated leukemia-producing capacity. Material from these cultures prepared from normal BALB/ c mouse tissue was used to immunize isologous mice against subsequent challenge with fully active Rauscher virus. The centrifuged supernatant of the culture had some immunizing properties. However, the most efficient protectionwas obtained when cell suspensions from these cultures were used in the form of a series of three intraperitoneal and intramuscular injections and onebooster injection.

    Keywords:
    EXPERIMENTAL LAB STUDYLEUKEMIA, EXPERIMENTALMICEMOUSE LEUKEMIA VIRUSESNEOPLASM IMMUNOLOGYONCOGENIC VIRUSESSPLEENTHYMUS GLANDTISSUE CULTURE

    More Related Videos

    Myeloid Cell Isolation from Mouse Skin and Draining Lymph Node Following Intradermal Immunization with Live Attenuated Plasmodium Sporozoites08:46

    Myeloid Cell Isolation from Mouse Skin and Draining Lymph Node Following Intradermal Immunization with Live Attenuated Plasmodium Sporozoites

    Published on: May 18, 2016

    High-Efficiency Generation of Antigen-Specific Primary Mouse Cytotoxic T Cells for Functional Testing in an Autoimmune Diabetes Model11:31

    High-Efficiency Generation of Antigen-Specific Primary Mouse Cytotoxic T Cells for Functional Testing in an Autoimmune Diabetes Model

    Published on: August 16, 2019

    Related Concept Videos

    Cell-mediated Immune Responses01:40

    Cell-mediated Immune Responses

    Overview
    Vaccinations01:51

    Vaccinations

    Overview
    Vaccines01:21

    Vaccines

    Vaccines are among the most effective tools in preventive medicine, designed to prepare the immune system to recognize and combat infectious agents. By introducing antigens—substances that the immune system identifies as foreign—vaccines stimulate an adaptive immune response that leads to immunological memory. This immunological memory enables the body to mount a faster and more effective response upon future exposures to the actual pathogen.Vaccines can be categorized based on the type of...