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Orthotopic Rat Kidney Transplantation: A Novel and Simplified Surgical Approach
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Orthotopic Rat Kidney Transplantation: A Novel and Simplified Surgical Approach

Published on: May 7, 2019

ERYTHROPOIESIS AND RENAL HOMOTRANSPLANTATION

P B MCMAIN, G C HOFFMAN, S NAKAMOTO

    Canadian Medical Association Journal
    |August 7, 1965
    PubMed

    Following the successful replacement of diseased kidneys by renal homotransplants, regression of the anemia of chronic renal disease was found in five patients. Increased erythropoietic-stimulating activity was demonstrated in the serum of one patient seven weeks after renal transplantation when he suffered a severe hemorrhage. It is postulated that a renal homotransplant can produce enough erythropoietin to maintain a normal hemoglobin value and to respond to the stimulus of a sudden hemorrhage.

    Keywords:
    ANEMIAERYTHROCYTE COUNTERYTHROPOIESISHEMORRHAGEKIDNEY DISEASESKIDNEY TRANSPLANTATIONPOSTOPERATIVE COMPLICATIONSRETICULOCYTESTRANSPLANTATION, HOMOLOGOUS

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