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A BENZOYL PEROXIDE-SULFUR CREAM FOR ACNE VULGARIS
Canadian Medical Association Journal
|August 7, 1965
Summary
This study shows that a benzoyl peroxide and sulfur combination effectively treats acne vulgaris, offering a safe and affordable alternative to other therapies. The medication rapidly reduces acne lesions with minimal side effects, primarily mild allergic sensitivity.
Area of Science:
- Dermatology
- Pharmacology
Background:
- Acne vulgaris is a common skin condition requiring effective treatment.
- Traditional acne therapies include radiation, light, and systemic antibiotics, which may have drawbacks.
Purpose of the Study:
- To evaluate the efficacy and safety of a benzoyl peroxide and sulfur combination for acne vulgaris treatment.
Main Methods:
- A combination of benzoyl peroxide and sulfur in an oil-in-water emulsion was applied to 286 acne patients.
- The medication was assessed for its ability to suppress acne lesions and for adverse reactions.
Main Results:
- The benzoyl peroxide and sulfur formulation effectively suppressed all types of acne lesions.
- The treatment eliminated the need for adjunctive therapies like x-ray, UV light, and systemic antibiotics.
- Contact allergic sensitivity occurred in 2.5% of patients, with no other adverse reactions noted.
Conclusions:
- Benzoyl peroxide and sulfur in an oil-in-water emulsion provide a safe, effective, and inexpensive treatment for acne vulgaris.
- This formulation offers a favorable alternative to existing acne therapies, with a low incidence of adverse effects.