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Related Experiment Videos

[Abnormalities in acid-base balance in the elderly].

T Nabata1, S Morimoto, T Ogihara

  • 1Department of Geriatric Medicine, Osaka University Medical School.

Nihon Rinsho. Japanese Journal of Clinical Medicine
|September 1, 1992
PubMed
Summary

Aging impairs the body's ability to regulate acid-base balance, increasing disease risk. This review details age-related changes in pH regulation, focusing on kidney and lung function decline and common acid-base disturbances in older adults.

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Area of Science:

  • Gerontology
  • Physiology
  • Nephrology

Context:

  • Physiological aging leads to reduced acid-base regulatory capacity.
  • Elderly individuals often have comorbidities like renal insufficiency and chronic obstructive pulmonary disease.
  • Medications, including diuretics, can significantly impact acid-base balance in older populations.

Purpose:

  • To describe the unique characteristics of acid-base balance abnormalities in the elderly.
  • To highlight the physiological decline affecting pH regulation with aging.
  • To review common metabolic and respiratory acid-base disturbances in older adults.

Summary:

  • Aging diminishes the kidney and lung's ability to maintain acid-base homeostasis.
  • Reduced organ function and increased disease prevalence in the elderly exacerbate acid-base disturbances.

Related Experiment Videos

  • This paper outlines the clinical features of metabolic and respiratory acidosis and alkalosis in aging individuals.

    • Impact:

    • Provides a comprehensive overview of age-related acid-base disturbances for clinicians.
    • Enhances understanding of pathophysiological changes affecting pH balance in geriatrics.
    • Informs clinical management strategies for acid-base disorders in the elderly.