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Related Experiment Videos

Ocular dimensions with aging in normal eyes.

K J Lim1, S M Hyung, D H Youn

  • 1Department of Ophthalmology, College of Medicine, Seoul National University, Korea.

Korean Journal of Ophthalmology : KJO
|June 1, 1992
PubMed
Summary

Aging increases lens thickness and decreases anterior chamber depth in both sexes. Females experience accelerated changes after age 40, suggesting a higher risk of angle closure glaucoma in older women.

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Area of Science:

  • Ophthalmology
  • Anatomical studies
  • Gerontology

Background:

  • The anterior segment of the eye undergoes dynamic changes with age.
  • Understanding these changes is crucial for diagnosing and managing age-related ocular conditions.

Purpose of the Study:

  • To quantify age- and sex-related changes in anterior chamber depth (ACD) and lens thickness (LT).
  • To investigate the ratio of ACD to axial length across different age groups and sexes.
  • To predict the prevalence of angle closure glaucoma based on these anatomical changes.

Main Methods:

  • Contact ultrasonography and anterior chamber photography were used to measure ACD and LT.
  • Data were collected from 141 women (241 eyes) and 76 men (130 eyes) aged 10–70 years.
  • Statistical analysis was performed to compare measurements between sexes and age groups.

Main Results:

  • Lens thickness increased and ACD decreased with aging in both sexes.
  • Females showed an accelerated decrease in ACD between their 40s and 50s.
  • The ratio of ACD to axial length was smaller in females than males after age 50.

Conclusions:

  • Aging significantly alters ocular anatomy, particularly in the anterior segment.
  • Females are at a higher risk for angle closure glaucoma post-middle age due to these anatomical shifts.
  • These findings highlight the importance of age- and sex-specific considerations in glaucoma screening and management.

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