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Robotic D3 Partial Duodenal Resection with Primary Side-to-Side Anastomosis
Published on: December 15, 2023
Noncurative resection for advanced gastric cancer
Y Maehara1, Y Kakeji, I Takahashi
1Department of Surgery II, Faculty of Medicine, Kyushu University, Fukuoka, Japan.
Journal of Surgical Oncology
|December 1, 1992
Summary
Patients with noncurative gastric cancer resection were analyzed. Locally advanced disease had better outcomes than distant metastasis, suggesting aggressive surgery and chemotherapy are vital for advanced gastric cancer survival.
Area of Science:
- Oncology
- Surgical Oncology
- Gastroenterology
Background:
- Advanced gastric cancer presents significant treatment challenges.
- Noncurative resection, defined by residual tumor cells post-gastric resection, impacts patient prognosis.
- Understanding clinicopathological features is crucial for advanced gastric cancer management.
Purpose of the Study:
- To examine the clinicopathological features and prognosis of patients with advanced gastric cancer.
- To compare outcomes between locally advanced gastric cancer and gastric cancer with distant metastasis.
- To evaluate the impact of surgical management on survival in noncurative gastric cancer cases.
Main Methods:
- Retrospective analysis of 489 patients with advanced gastric cancer undergoing gastric resection between 1965 and 1985.
- Classification of patients into two groups: locally advanced cancer and cancer with distant metastasis.
- Evaluation of clinicopathological factors including serosal invasion, lymph node metastasis, and lymphatic involvement.
Main Results:
- Both locally advanced and distant metastasis groups showed prominent serosal invasion and high rates of lymph node and lymphatic involvement.
- Patients with locally advanced gastric cancer demonstrated a significantly better survival rate compared to those with distant metastasis (P < 0.01).
- Survival time in locally advanced gastric cancer could be improved by maximizing tumor and metastatic lesion resection.
Conclusions:
- Surgical resection, even when noncurative, can improve survival in locally advanced gastric cancer.
- Aggressive postoperative chemotherapy is recommended for patients with distant metastasis from gastric cancer.
- Differentiating between locally advanced disease and distant metastasis is critical for guiding treatment strategies in advanced gastric cancer.
