The dioxopiperazine derivatives, their leukemogenic potential and other biological effects

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Genetics of therapy-related myelodysplasia and acute myeloid leukemia.

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Alternative genetic pathways and cooperating genetic abnormalities in the pathogenesis of therapy-related myelodysplasia and acute myeloid leukemia.

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Mutations of genes in the receptor tyrosine kinase (RTK)/RAS-BRAF signal transduction pathway in therapy-related myelodysplasia and acute myeloid leukemia.

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Amplification or duplication of chromosome band 21q22 with multiple copies of the AML1 gene and mutation of the TP53 gene in therapy-related MDS and AML.

Leukemia·2004

Methylation of p15INK4B is common, is associated with deletion of genes on chromosome arm 7q and predicts a poor prognosis in therapy-related myelodysplasia and acute myeloid leukemia.

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Cladribine-based salvage therapy in relapsed/refractory AML: A multicenter retrospective study.

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Stemness-driven INTS7 overexpression links metabolic comorbidity to chemoresistance in acute myeloid leukemia with type 2 diabetes.

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SLC1A5 and NUMA1 are potential regulators and therapeutic targets of ferroptosis in diffuse large B-cell lymphoma.

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Feasibility of blinatumomab in newly diagnosed pediatric B-cell acute lymphoblastic leukemia patients requiring modification of standard chemotherapy.

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Treatment outcome in pediatric patients with T-ALL in Brazil.

Leukemia research·2026

Arterial stiffness in patients with chronic myeloid leukemia receiving tyrosine kinase inhibitors: An exploratory prospective observational study.

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Clonal evolution from primary to locally recurrent rectal cancer reveals recurrence-acquired potentially actionable alterations in treatment-naïve tumors.

Journal of gastroenterology·2026

Linking Early and Late Endpoints in Adjuvant Immunotherapy Trials: An Evaluation of Multiple Clinical Outcomes.

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Reproducibility of overall survival in metastatic colorectal cancer randomized trials using ARCAD-Derived external control arms.

Journal of the National Cancer Institute·2026

Trajectory Patterns of Perioperative Anxiety and Depressive Symptoms in Patients With Digestive System Malignancies and Their Impact on Postoperative Outcomes.

Actas espanolas de psiquiatria·2026

Extracellular vesicles and their translational therapeutic potential.

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Dynamic Procalcitonin Trajectories Predict Adverse Outcomes in Acute-on-Chronic Pancreatitis.

Cureus·2026

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NPM1 mutations in therapy-related acute myeloid leukemia with uncharacteristic features.

Genetics of therapy-related myelodysplasia and acute myeloid leukemia.

Alternative genetic pathways and cooperating genetic abnormalities in the pathogenesis of therapy-related myelodysplasia and acute myeloid leukemia.

Mutations of genes in the receptor tyrosine kinase (RTK)/RAS-BRAF signal transduction pathway in therapy-related myelodysplasia and acute myeloid leukemia.

Amplification or duplication of chromosome band 21q22 with multiple copies of the AML1 gene and mutation of the TP53 gene in therapy-related MDS and AML.

Methylation of p15INK4B is common, is associated with deletion of genes on chromosome arm 7q and predicts a poor prognosis in therapy-related myelodysplasia and acute myeloid leukemia.

Cladribine-based salvage therapy in relapsed/refractory AML: A multicenter retrospective study.

Stemness-driven INTS7 overexpression links metabolic comorbidity to chemoresistance in acute myeloid leukemia with type 2 diabetes.

SLC1A5 and NUMA1 are potential regulators and therapeutic targets of ferroptosis in diffuse large B-cell lymphoma.

Feasibility of blinatumomab in newly diagnosed pediatric B-cell acute lymphoblastic leukemia patients requiring modification of standard chemotherapy.

Treatment outcome in pediatric patients with T-ALL in Brazil.

Arterial stiffness in patients with chronic myeloid leukemia receiving tyrosine kinase inhibitors: An exploratory prospective observational study.

Clonal evolution from primary to locally recurrent rectal cancer reveals recurrence-acquired potentially actionable alterations in treatment-naïve tumors.

Linking Early and Late Endpoints in Adjuvant Immunotherapy Trials: An Evaluation of Multiple Clinical Outcomes.

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