Non-selectivity of new bradykinin antagonists for B1 receptors

Are you better? A multi-centre study of patient-defined recovery from Complex Regional Pain Syndrome.

European journal of pain (London, England)·2017

Bradykinin B₂ receptors increase hippocampal excitability and susceptibility to seizures in mice.

Neuroscience·2013

High salt-induced hypertension in B2 knockout mice is corrected by the ETA antagonist, A127722.

British journal of pharmacology·2013

VRQ397 (CRAVKY): a novel noncompetitive V2 receptor antagonist.

American journal of physiology. Regulatory, integrative and comparative physiology·2009

Therapeutic options in inflammatory bowel disease: experimental evidence of a beneficial effect of kinin B1 receptor blockade.

British journal of pharmacology·2008

Neuropeptide S is a stimulatory anxiolytic agent: a behavioural study in mice.

British journal of pharmacology·2008

Probiotic mixture ameliorates cisplatin-induced kidney injury by reducing uremic toxins and modulating the gut microbiota.

Life sciences·2026

Disruption of CTCF-mediated IGF2 repression promotes AKT-dependent mitochondrial oxidative stress and chondrocyte senescence in osteoarthritis.

Life sciences·2026

Targeting IGF2BP3-driven CSF1/CSF1R signaling disrupts the positive feedback loop between tumor cells and macrophages and inhibits HCC progression.

Life sciences·2026

Endothelial cell LGR4 maintains liver sinusoidal endothelial cell Identity and protects against hepatic steatosis.

Life sciences·2026

NAMPT activation protects against myocardial ischemia/reperfusion injury via FSP1-CoQ10 ferroptosis defense.

Life sciences·2026

Ebselen sensitizes multidrug-resistant cancer cells to doxorubicin by disrupting cellular redox homeostasis and inducing ferroptosis.

Life sciences·2026

Local anesthetic systemic toxicity with liposomal bupivacaine: a case series and literature review.

BMC anesthesiology·2026

Treatment of Isolated Nail Psoriasis with JAK Inhibitor Tofacitinib: A Case Report.

Clinical, cosmetic and investigational dermatology·2026

Toxicological and pharmacodynamic evaluation of Nixodine-S [(S)-6-Methylnicotine] relative to (S)-nicotine.

Toxicology reports·2026

Correction: Barros et al. Effects of Eriobotrya japonica (Thunb.) Lindl. Leaf Extract on Zebrafish Embryogenesis, Behavior, and Biochemical Pathways. Molecules 2025, 30, 3252.

Molecules (Basel, Switzerland)·2026

Correction: Almeida et al. Diterpenes: Nature's Hidden Gems of Immunomodulation. Int. J. Mol. Sci. 2025, 26, 2250.

International journal of molecular sciences·2026

Corrigendum to: The Integration of Systematic Pharmacology and Experimental Validation to Explain the Mechanism of Action of Wuling Capsule in the Treatment of NAFLD.

Combinatorial chemistry & high throughput screening·2026

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Non-selectivity of new bradykinin antagonists for B1 receptors

Related Concept Videos

Are you better? A multi-centre study of patient-defined recovery from Complex Regional Pain Syndrome.

Bradykinin B₂ receptors increase hippocampal excitability and susceptibility to seizures in mice.

High salt-induced hypertension in B2 knockout mice is corrected by the ETA antagonist, A127722.

VRQ397 (CRAVKY): a novel noncompetitive V2 receptor antagonist.

Therapeutic options in inflammatory bowel disease: experimental evidence of a beneficial effect of kinin B1 receptor blockade.

Neuropeptide S is a stimulatory anxiolytic agent: a behavioural study in mice.

Probiotic mixture ameliorates cisplatin-induced kidney injury by reducing uremic toxins and modulating the gut microbiota.

Disruption of CTCF-mediated IGF2 repression promotes AKT-dependent mitochondrial oxidative stress and chondrocyte senescence in osteoarthritis.

Targeting IGF2BP3-driven CSF1/CSF1R signaling disrupts the positive feedback loop between tumor cells and macrophages and inhibits HCC progression.

Endothelial cell LGR4 maintains liver sinusoidal endothelial cell Identity and protects against hepatic steatosis.

NAMPT activation protects against myocardial ischemia/reperfusion injury via FSP1-CoQ10 ferroptosis defense.

Ebselen sensitizes multidrug-resistant cancer cells to doxorubicin by disrupting cellular redox homeostasis and inducing ferroptosis.

Local anesthetic systemic toxicity with liposomal bupivacaine: a case series and literature review.

Treatment of Isolated Nail Psoriasis with JAK Inhibitor Tofacitinib: A Case Report.

Toxicological and pharmacodynamic evaluation of Nixodine-S [(S)-6-Methylnicotine] relative to (S)-nicotine.

Correction: Barros et al. Effects of Eriobotrya japonica (Thunb.) Lindl. Leaf Extract on Zebrafish Embryogenesis, Behavior, and Biochemical Pathways. Molecules 2025, 30, 3252.

Correction: Almeida et al. Diterpenes: Nature's Hidden Gems of Immunomodulation. Int. J. Mol. Sci. 2025, 26, 2250.

Corrigendum to: The Integration of Systematic Pharmacology and Experimental Validation to Explain the Mechanism of Action of Wuling Capsule in the Treatment of NAFLD.

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Non-selectivity of new bradykinin antagonists for B1 receptors

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