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Therapeutic potential of capsaicin-like molecules: studies in animals and humans
1Pharmacology Department, A. Menarini Pharmaceuticals, Florence, Italy.
Life Sciences
|January 1, 1992
Abstract:
Capsaicin-sensitive primary afferent neurons in the peripheral nervous system are widely distributed to both the somatic and visceral territories: their inactivation following capsaicin "desensitization" is expected to produce analgesia and to be useful for a number of human diseases such as asthma, urinary incontinence, inflammatory diseases of the gut, arthritis and psoriasis. The present communication reviews the therapeutic potential of capsaicin-like drugs in the pathophysiology of the mammalian urinary bladder.