Congestive cardiomyopathy in Noonan's syndrome

We report a clinicopathologic study of intractable congestive cardiomyopathy in a teenaged patient who had features of Noonan's syndrome. Various forms of congenital cardiac malformations occur commonly in Noonan's syndrome, and there are also a few reported cases of cardiomyopathy in this entity. Unlike previously documented cases, our patient was found at autopsy to have nonobstructive hypertrophic cardiomyopathy.