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[Epigastric colic after ceftriaxone therapy].

E Sorantin1, R Fotter, K A Hausegger

  • 1Universitätsklinik für Radiologie, Graz.

Monatsschrift Kinderheilkunde : Organ Der Deutschen Gesellschaft Fur Kinderheilkunde
|August 1, 1992
PubMed
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Ceftriaxone therapy for meningitis can cause gallbladder sludge in children. Follow-up ultrasounds showed normal gallbladder function, suggesting a temporary side effect.

Area of Science:

  • Pediatric Gastroenterology
  • Pharmacology
  • Medical Imaging

Background:

  • Purulent meningitis requires prompt antibiotic treatment.
  • Ceftriaxone is a common antibiotic used for bacterial meningitis.
  • Abdominal pain is a potential adverse effect of various medications.

Observation:

  • A pediatric patient presented with right upper quadrant abdominal colic.
  • The colic occurred subsequent to Ceftriaxone therapy for purulent meningitis.
  • Ultrasound revealed sludge-balls within the gallbladder.

Findings:

  • Gallbladder sludge formation is a notable side effect of Ceftriaxone.
  • The observed gallbladder precipitations were transient.
  • Follow-up ultrasonography demonstrated a normal gallbladder.

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Implications:

  • Clinicians should be aware of potential gallbladder-related side effects of Ceftriaxone.
  • Gallbladder sludge associated with Ceftriaxone may be reversible.
  • Further investigation into the mechanism and clinical significance of Ceftriaxone-induced gallbladder precipitation is warranted.