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[Hepatitis E now also in The Netherlands].

H J van der Pal1, P L Jansen

  • 1Afd. Interne Geneeskunde, Academisch Medisch Centrum, Amsterdam.

Nederlands Tijdschrift Voor Geneeskunde
|October 31, 1992
PubMed
Summary
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A traveler returned from Bangladesh with symptoms mimicking acute hepatitis A. Diagnostic investigation confirmed a diagnosis of hepatitis E infection, with complete recovery within two weeks.

Area of Science:

  • Hepatology
  • Infectious Diseases
  • Travel Medicine

Background:

  • Hepatitis E virus (HEV) is a significant cause of acute viral hepatitis globally, particularly in resource-limited settings.
  • Travelers returning from endemic areas are at risk of acquiring HEV infection.
  • Distinguishing HEV from other hepatitis viruses, such as Hepatitis A virus (HAV), can be challenging based on clinical presentation alone.

Observation:

  • A 31-year-old male presented with clinical features suggestive of acute hepatitis A following a trip to Bangladesh.
  • Initial symptoms included jaundice and malaise, consistent with viral hepatitis.
  • The patient's travel history to a region with endemic Hepatitis E was a key factor in the differential diagnosis.

Findings:

  • Serological testing and molecular assays confirmed the diagnosis of acute hepatitis E infection.

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  • Hepatitis A virus infection was ruled out through specific diagnostic markers.
  • The patient experienced a self-limiting illness with clinical resolution.

    • Implications:

    • This case highlights the importance of considering hepatitis E in travelers returning from endemic regions, even when symptoms resemble hepatitis A.
    • Accurate diagnosis of hepatitis E is crucial for appropriate patient management and public health surveillance.
    • Awareness among clinicians regarding the differential diagnosis of viral hepatitis in travelers is essential for timely and correct diagnosis.