[The modulation of the functional properties of the skin thermoreceptors]

The characteristic property of skin cold receptors is the presence of static and dynamic activity with their maximum at any skin temperature. Parallel with the common properties there are some differences in the temperature range of receptors' functioning, frequency of static and dynamic activity, concentration of sensitive receptors on the skin. Mechanisms of these differences are unknown. It is found that the character of skin cold receptors functioning can be changed in individual life of the organism. Some parameters of static and dynamic activity as well as concentration of cold receptors functioning change both with adaptation of the organism to cold and with a rise of the noradrenaline concentration in blood. The reason of adaptive modifications of skin thermoreceptors may be an increase of their sensitivity to noradrenaline observed with adaptation to cold. It can be supposed that the modulating influence of biological active substances is very important in forming activity and sensitivity of skin thermoreceptors.