Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Future directions in antimicrobial chemotherapy.

R Janknegt1

  • 1Department of Clinical Pharmacy and Toxicology, Maasland Hospital, Sittard, The Netherlands.

Pharmaceutisch Weekblad. Scientific Edition
|August 21, 1992
PubMed
Summary

New antibiotics like cephalosporins, carbapenems, fluoroquinolones, and macrolides offer improved treatments for bacterial infections, targeting both Gram-positive and Gram-negative bacteria effectively.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

The nocebo effect challenges the non-medical infliximab switch in practice.

European journal of clinical pharmacology·2018
Same author

The use of an electronic clinical rule to discontinue chronically used benzodiazepines and related Z drugs.

European journal of clinical pharmacology·2017
Same author

Usually Available Clinical and Laboratory Data Are Insufficient for a Valid Medication Review: A Crossover Study.

The journal of nutrition, health & aging·2016
Same author

SWAB/NVALT (Dutch Working Party on Antibiotic Policy and Dutch Association of Chest Physicians) guidelines on the management of community-acquired pneumonia in adults.

The Netherlands journal of medicine·2012
Same author

[Optimisation of the antibiotic policy in the Netherlands. X. The SWAB guideline for antimicrobial treatment of complicated urinary tract infections].

Nederlands tijdschrift voor geneeskunde·2006
Same author

[Optimizing the antibiotics policy in The Netherlands. VIII. Revised SWAB guidelines for antimicrobial therapy in adults with community-acquired pneumonia].

Nederlands tijdschrift voor geneeskunde·2005

Area of Science:

  • Pharmacology
  • Infectious Diseases
  • Microbiology

Background:

  • Bacterial infections pose a significant global health challenge.
  • The emergence of antibiotic resistance necessitates the development of novel therapeutic agents.

Purpose of the Study:

  • To review recent advancements in antimicrobial agents for treating bacterial infections.
  • To highlight key characteristics and potential applications of new antibiotic classes.

Main Methods:

  • Literature review of new antibiotic developments.
  • Analysis of antimicrobial activity spectra and pharmacokinetic properties.

Main Results:

  • Oral broad-spectrum cephalosporins and extended-spectrum injectable cephalosporins show enhanced Gram-positive activity.
  • Meropenem, a carbapenem, demonstrates improved efficacy against Gram-negative bacteria.
  • New fluoroquinolones, including sparfloxacin, and the macrolide azithromycin with its long half-life are under development.

Conclusions:

  • Novel antibiotic agents offer promising therapeutic options for various bacterial infections.
  • These developments are crucial for combating evolving antimicrobial resistance patterns.

Related Experiment Videos