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Characterization of Leukocyte-platelet Rich Fibrin, A Novel Biomaterial
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[Blood coagulation and fibrinolysis in blood donors after plasmapheresis]

B Zukowska1, M Kotschy

  • 1Katedry i Zakładu Patofizjologii AM, Bydgoszczy.

Polski Tygodnik Lekarski (Warsaw, Poland : 1960)
|February 3, 1992
PubMed

Authors were interested in blood coagulation proteins and fibrinolysis in blood donors following several plasmaphereses. This interest was related to the occurrence of thrombo-embolic and hemorrhagic complications in these subjects. Blood morphology, serum protein, blood coagulation and fibrinolysis have been examined in 40 healthy blood donors, aged between 19 and 46 years, who gave blood plasma by plasmapheresis technique for 1-59 times. Results did not show any significant changes in blood morphology and serum protein levels prior to and after consecutive plasmaphereses. No significant decrease in blood coagulation proteins and fibrinolysis has been noted. However, a significant increase in factors VIII and IX activities was noted in several blood donors, who underwent the largest number of plasmaphereses. It may predispose these donors to thrombo-embolic complications.

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