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Effects of peripheral hormones on memory and ingestive behaviors
J E Morley1, J Flood, A J Silver
1Geriatric Research, Education, and Clinical Center, St. Louis Department of Veterans Affairs, Missouri.
Psychoneuroendocrinology
|August 1, 1992
Abstract:
This article explores the mechanisms by which peripheral gastrointestinal hormones produce central nervous system effects on memory and feeding. Cholecystokinin produces its satiety effects and memory-enhancing effects by stimulating ascending vagal fibers. Hyperglycemia has been demonstrated to be a cause of memory dysfunction in persons with diabetes mellitus. A number of other hormones, such as amylin and bombesin, modulate both memory processing and feeding. The causes of the anorexia of aging are briefly reviewed.