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Updated: Aug 10, 2026

Anatomical Reconstructions of the Human Cardiac Venous System using Contrast-computed Tomography of Perfusion-fixed Specimens
Published on: April 18, 2013
[Cardiac performance in total anomalous pulmonary venous connection]
H Fukushima1, S Satou, I Satou
1Department of Pediatrics, Niigata University School of Medicine.
Preoperative cardiac function, including left ventricular ejection fraction (LVEF), was better in patients who survived total anomalous pulmonary venous connection repair. Post-operative performance in survivors was generally normal.
Area of Science:
- Cardiology
- Pediatric Cardiac Surgery
- Congenital Heart Disease
Context:
- Total anomalous pulmonary venous connection (TAPVC) is a complex congenital heart defect.
- Surgical repair outcomes are influenced by preoperative cardiac status.
- Understanding predictors of survival is crucial for patient management.
Purpose:
- To evaluate cardiac performance before and after surgical repair in TAPVC patients.
- To identify preoperative indicators of surgical survival.
- To assess postoperative cardiac function in survivors.
Summary:
- Cardiac catheterization was performed on 54 TAPVC patients pre- and post-surgery.
- Survivors had significantly higher preoperative left ventricular ejection fraction (LVEF) and lower pulmonary arterial pressure compared to non-survivors.
- Postoperative LVEF and left ventricular end-diastolic volume (LVEDV) improved, while right ventricular ejection fraction (RVEF), RVEDV, and pulmonary arterial pressure decreased.
Impact:
- Preoperative cardiac function is a significant predictor of mortality in TAPVC repair.
- Surgical repair leads to improved left ventricular function and normalized hemodynamics in survivors.
- Findings inform risk stratification and surgical decision-making for TAPVC patients.
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