Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Epithelial adherence to polytetrafluoroethylene (PTFE) material.

H J Grevstad1, K N Leknes

  • 1Department of Periodontology, School of Dentistry, University of Bergen, Norway.

Scandinavian Journal of Dental Research
|August 1, 1992
PubMed
Summary

Epithelial cells attach to polytetrafluoroethylene (PTFE) membranes used in guided tissue regeneration. However, this adherence involves cellular degeneration and lacks true attachment complexes, indicating limited biocompatibility.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

The effect of smoking on inflammatory and bone remodeling markers in gingival crevicular fluid and subgingival microbiota following periodontal therapy.

Journal of periodontal research·2017
Same author

Mapping of titanium particles in peri-implant oral mucosa by laser ablation inductively coupled plasma mass spectrometry and high-resolution optical darkfield microscopy.

Journal of oral pathology & medicine : official publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology·2010
Same author

Coronally positioned flap procedures with or without a bioabsorbable membrane in the treatment of human gingival recession.

Journal of periodontology·2000
Same author

Oral tissue reactions to suture materials.

The International journal of periodontics & restorative dentistry·1999
Same author

Recurrence of mandibular molar furcation defects following citric acid root treatment and coronally advanced flap procedures.

The International journal of periodontics & restorative dentistry·1998
Same author

The influence of anatomic and iatrogenic root surface characteristics on bacterial colonization and periodontal destruction: a review.

Journal of periodontology·1997

Area of Science:

  • Biomaterials Science
  • Periodontology
  • Cell Biology

Background:

  • Guided tissue regeneration (GTR) utilizes barrier membranes to facilitate periodontal healing.
  • Polytetrafluoroethylene (PTFE) is a material employed in GTR membranes.
  • Understanding cellular interactions with biomaterials is crucial for optimizing regenerative therapies.

Purpose of the Study:

  • To investigate the adherence and attachment characteristics of gingival epithelial cells to PTFE material.
  • To specifically analyze the nature of epithelial cell interaction with PTFE membranes used in GTR.

Main Methods:

  • Transmission electron microscopy (TEM) was used to examine retrieved Gore-Tex (PTFE) membranes.
  • Membranes were collected from patients after 30 days of healing following periodontal treatment.

Related Experiment Videos

  • Cellular adherence and ultrastructural features were analyzed in prepared membrane segments.

    • Main Results:

    • Most PTFE membrane segments showed minimal tissue adherence, primarily erythrocytes and polymorphonuclear cells.
    • Epithelial cell adherence occurred via a thin acellular layer, not direct cellular attachment.
    • Adhering epithelial cells displayed signs of degeneration, including cytoplasmic condensation and vacuolization.

    Conclusions:

    • Epithelial cells adhere to PTFE material but do not form true attachment complexes.
    • The observed cellular degeneration suggests limited biocompatibility of PTFE for epithelial cell integration.
    • Further research is needed to develop PTFE modifications or alternative materials that promote better cellular integration in GTR.