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Idiopathic constipation: any movement?
1Medical Physiology Unit, St Mark's Hospital, London, U.K.
Scandinavian Journal of Gastroenterology. Supplement
|January 1, 1992
Summary
Severe constipation research has advanced, distinguishing patient subgroups and identifying colonic neurotransmitter abnormalities. Biofeedback therapy shows promise for treating specific constipation types.
Area of Science:
- Gastroenterology
- Colorectal Research
Background:
- Severe constipation is a growing research focus with recent advancements.
- Understanding patient subgroups with distinct epidemiologies, symptoms, causes, and treatments is improving.
Purpose of the Study:
- To review recent advances in understanding and treating severe constipation.
- To highlight the differentiation of various constipation-related conditions.
Main Methods:
- Utilizing radioisotope transit studies for detailed gastrointestinal evaluation.
- Incorporating psychologic assessments.
- Analyzing colonic neurotransmitter abnormalities and pathologic findings in specific patient groups.
Main Results:
- Subgroups of constipation patients can now be distinguished.
- Decreased propulsive mass movements and colonic neurotransmitter abnormalities identified in young women with idiopathic constipation.
- Biofeedback therapy is effective for many patients; surgical outcomes are clarified.
Conclusions:
- Severe constipation comprises diverse conditions, necessitating precise diagnosis.
- Advances in understanding pathogenesis and treatment are emerging.
- Personalized treatment approaches are becoming more feasible.