[Induced cell fusion in a heteroploid cell line]

Non-uniformity in properties of the cells within the stabilized heterocaryonic line is certified by the decrease in capacity of the cells to fuse together after repeated influence of polyethylene glycol. Multiple and large polycaryonic formations resulting from primary administration of fusogen are relatively rapid in extinction. The cells having been survived after repeated administration of polyethylene glycol appear to fuse predominantly into less extended polycaryocytes with smaller multiplicity. This fact may be a consequence of the selection of a portion of non-uniform cell population being more susceptible to this fusogen. Those concerned are probably the cells rather different in surface qualities and/or adjacent parts of cytoskeleton.