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[Kikuchi-Fujimoto necrotizing lymphadenitis associated with brucellosis]
J Rodríguez Martorell1, M V Martín, J M Báez
1Servicio de Hematología-Hemoterapia, Hospital Clínico-Universitario Puerta del Mar, Cádiz.
Sangre
|June 1, 1992
Summary
This case study highlights a rare association between Kikuchi's disease and brucellosis in a young woman. Prompt diagnosis and treatment led to a full recovery, underscoring the importance of considering infections in lymphadenitis differential diagnoses.
Area of Science:
- Infectious Diseases
- Pathology
- Internal Medicine
Background:
- Hodgkin's disease is a common malignancy diagnosed via lymph node biopsy.
- Fever and sweats are common symptoms that can indicate various underlying conditions.
- Kikuchi's necrotising lymphadenitis is a rare, benign condition that can mimic lymphoma.
Observation:
- A 22-year-old woman presented with fever and sweats, initially suspected of having Hodgkin's disease.
- Review of lymph node biopsy revealed Kikuchi's necrotising lymphadenitis.
- Microbiological and serologic tests confirmed coexisting brucellosis.
Findings:
- Brucellosis, an infection, was identified as a potential trigger or co-factor in Kikuchi's disease.
- The patient's symptoms resolved completely after treatment with streptomycin and doxycycline.
- One-year follow-up showed no recurrence of symptoms or lymphadenopathy.
Implications:
- This case expands the known infectious associations of Kikuchi's disease.
- It emphasizes the need to rule out infections like brucellosis in patients presenting with symptoms suggestive of lymphoma.
- Accurate diagnosis is crucial to avoid misclassification as malignant lymphoma and ensure appropriate treatment.