Common granulomatous inflammations of the extremities

Granulomatous inflammatory diseases of the extremities caused by inanimate agents (physical or chemical) and agents of unknown character are frequently unrecognized. The symptoms produced by these lesions are too frequently ascribed to trauma, particularly an insignificant bruise or imagined microtrauma. None of the rheumatic diseases-tenosynovitis, myositis, bursitis, fibrositis, gout, rheumatoid arthritis and osteoarthritis-has ever been created by slight or severe mechanical trauma in experimental animals or human beings.