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Leishmaniasis in Mediterranean countries
1Laboratoire Central, Centre Hospitalo-Universitaire Parnet, Hussein-dey, Algeria.
Veterinary Parasitology
|September 1, 1992
Summary
Mediterranean leishmaniasis is spreading geographically, with recrudescent zoonoses noted. Challenges in developing vaccines for visceral and cutaneous leishmaniasis in humans and dogs persist, despite isoenzyme identification of causative agents.
Area of Science:
- Epidemiology
- Zoonotic diseases
- Parasitology
Background:
- Leishmaniasis, a zoonotic disease, presents both visceral and cutaneous forms.
- Mediterranean countries are experiencing a resurgence and geographical expansion of leishmaniasis.
- Current epidemiological data highlights the need for effective control strategies.
Purpose of the Study:
- To describe the current epidemiology of leishmaniasis in Mediterranean regions.
- To present recent findings on the isoenzyme identification of Leishmania species.
- To discuss challenges in developing vaccines against leishmaniasis for humans and dogs.
Main Methods:
- Epidemiological data review.
- Isoenzyme analysis of Leishmania isolates.
- Vaccine development challenge assessment.
Main Results:
- Recrudescence and geographical spread of visceral and cutaneous leishmaniasis in the Mediterranean.
- Isoenzyme characterization of causative Leishmania species.
- Significant hurdles identified in creating effective human and canine leishmaniasis vaccines.
Conclusions:
- Leishmaniasis epidemiology in the Mediterranean is dynamic, requiring ongoing surveillance.
- Isoenzyme identification aids in understanding parasite diversity.
- Vaccine development for leishmaniasis remains a complex, unmet need.