Left bifascicular block with normally conducting middle fascicle
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Updated: Sep 2, 2026

High-Resolution Endocardial and Epicardial Optical Mapping in a Sheep Model of Stretch-Induced Atrial Fibrillation
Published on: July 29, 2011
Insights
A case study reveals left ventricular hypertrophy progression in aortic insufficiency. Over one year, ECG showed a new left bifascicular block, suggesting specific fascicle involvement in septal activation.
Area of Science:
- Cardiology
- Electrophysiology
- Cardiac Imaging
Background:
- Aortic insufficiency can lead to left ventricular hypertrophy (LVH) and strain.
- Electrocardiography (ECG) and Vectorcardiography (VCG) are crucial for assessing cardiac electrical activity.
Observation:
- A patient with aortic insufficiency initially presented with ECG findings of LVH and strain.
- Follow-up ECG and VCG recordings after one year demonstrated the development of a left bifascicular block.
Findings:
- The left bifascicular block involved the anterior and posterior fascicles.
- Septal activation remained normal, suggesting the middle fascicle's role in activating the inferior septum.
Implications:
- This case suggests a specific pattern of fascicular involvement in aortic insufficiency.
- The findings prompt further investigation into the electrophysiological mechanisms of septal activation in cardiac disease.
Abstract:
A case of aortic insufficiency showing an ECG pattern of left ventricular hypertrophy and strain has been followed over time. One year after the initial observation, the ECG and VCG recordings showed the appearance of a left bifascicular block, due to involvement of the anterior and posterior fascicles, with normal septal activation. It is suggested that the normally functioning middle fascicle activates the inferior two-thirds of the septum. This hypothesis is discussed in light of recent experimental data.
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