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Updated: Aug 19, 2026

Skeletal Muscle Gender Dimorphism from Proteomics
Published on: December 14, 2011
Changes in muscle fibre type from adolescence to adulthood in women and men
B Glenmark1, G Hedberg, E Jansson
1Department of Clinical Physiology, Karolinska Hospital, Stockholm, Sweden.
Abstract:
Age-related changes in muscle fibre characteristics have been presented in cross-sectional studies previously. The aim of the present study was to investigate longitudinally whether the muscle fibre type composition and muscle fibre area change from adolescence to adulthood. Fifty-five men and 28 women were studied at the age of 16 and again at the age of 27. Biopsies were taken from the vastus lateralis muscle and analysed for fibre types (I, IIA, IIB, IIC) and fibre areas. Different development of fibre type composition with increased age were seen in women and men: the type I percentage tended to increase in the women (51 +/- 9 to 55 +/- 12) and decrease significantly in the men (55 +/- 12 to 48 +/- 13). The fibre areas remained unchanged in both sexes. It is suggested that there is a sex-related fibre adaptation to increased age.
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