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Rho(D) genotype and red cell Rho(D) antigen content
The Rh(o)(D) content of red cells obtained from different individuals as determined with I(181) anti-Rh(o)(D) showed a bimodal distribution. Family studies indicate that the cells with the lower antigen content represent the heterozygous Rh(o)(D) state and that the cells with 1.6 times more Rh(o)(D) correspond to the homozygous state.
The Rh(o)(D) content of red cells obtained from different individuals as determined with I(181) anti-Rh(o)(D) showed a bimodal distribution. Family studies indicate that the cells with the lower antigen content represent the heterozygous Rh(o)(D) state and that the cells with 1.6 times more Rh(o)(D) correspond to the homozygous state.
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