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Copper supplementation in the rat: preliminary observations on the clinical, hematological and histopathological
P Cristofori1, A Terron, M Marella
1Laboratorio di Patologia, Università degli Studi, Verona, Italia.
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|January 1, 1992
Abstract:
Complete toxicological examinations in female rats fed an "anti-inflammatory" 200 ppm copper-containing diet for 30 and 58 days were performed. Copper was found to accumulate in liver, kidneys and paws; however, at the hematological, clinical chemical and histopathological levels, this treatment did not seem able to induce any toxic accumulation phenomenon in the examined rats.