Myocardial necrosis through chemical-calcic mechanism

An 18-day-old child is presented with a ventricular septal defect and aspiration bronchopneumonia with abscesses. An extensives myocardial necrosis with calcium deposits is also present. The authors think that the myocardial necrosis is a consequence of the calcium deposition on the mitochondria of myocardial fibres, favoured by the general and local changes, especially the heart hypoxia due to the combined action of the heart congenital diseases and of bronchopneumonia.