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Optic neuropathy in Hodgkin's disease
R M Siatkowski1, B L Lam, N J Schatz
1Bascom Palmer Eye Institute, Miami, Florida.
American Journal of Ophthalmology
|November 15, 1992
Summary
This case study highlights an unusual instance of isolated optic neuropathy in a patient with Hodgkin's disease in remission. Prompt treatment with radiotherapy and corticosteroids led to significant vision recovery, suggesting malignancy recurrence.
Area of Science:
- Ophthalmology
- Oncology
- Neurology
Background:
- Hodgkin's disease is a rare cause of infiltrative optic neuropathy.
- Optic neuropathy typically presents late in the disease course.
Observation:
- A 21-year-old man in clinical remission from Hodgkin's disease presented with isolated optic neuropathy.
- The patient experienced acute vision loss.
Findings:
- Treatment with radiotherapy and high-dose systemic corticosteroids resulted in dramatic vision improvement.
- The patient's condition improved significantly with the chosen therapeutic interventions.
Implications:
- Acute-onset optic neuropathy in patients with a history of lymphoproliferative disorders warrants investigation for malignancy recurrence.
- This case underscores the importance of considering neoplastic processes even during remission.