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Synaptophysin expression in "ependymal tumors" induced by ethyl-nitrosourea in rats
1Neurosurgical Department, Puerta de Hierro Clinic, Autonomous University, Madrid, Spain.
The American Journal of Pathology
|November 1, 1992
Abstract:
Synaptophysin expression was studied in seven "ependymomas" induced by transplacental administration of ethyl-nitrosourea in rats. In all the cases, strong positivity for synaptophysin was found on tumor cells. This finding supports previous studies suggesting that ENU-induced brain tumors considered to be ependymal neoplasms, are, in fact, primitive neuroectodermal tumors.