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Published on: February 23, 2014
[Pertussis. Study of an epidemic]
J I Montiano Jorge1, A Lazcoz Huarte, C Amiama Pérez de Villarreal
1Departamento de Pediatría, Hospital de Cruces, Baracaldo, Vizcaya.
Insights
Pertussis, or whooping cough, is highly contagious. Bordetella pertussis was confirmed in 64.5% of children, with infants under one year most susceptible and at highest risk for severe symptoms.
Area of Science:
- Pediatrics
- Infectious Diseases
- Microbiology
Context:
- Review of 46 children diagnosed with Pertussis in 1989.
- Focus on clinical presentation, diagnosis, and treatment outcomes.
Purpose:
- To analyze the diagnostic yield of Bordet-Gengou cultures for Pertussis.
- To identify age-related susceptibility and disease severity.
- To evaluate treatment efficacy and patient outcomes.
Summary:
- Bordetella pertussis was confirmed in 64.5% of cases via nasopharyngeal culture.
- Infants under one year (70%) and children over five years (20%) showed increased susceptibility.
- Infants under two months experienced severe symptoms like apnea, necessitating hospitalization.
Impact:
- Erythromycin and salbutamol were administered, with supportive care.
- No deaths or long-term medical sequelae were reported in the study cohort.
- Highlights the importance of timely diagnosis and treatment for Pertussis in children.
Abstract:
Forty-six children seen during 1989 with the clinical diagnosis of Pertussis are reviewed in this study. In 64.5% of the cases the Bordet-Gengou medium nasopharyngeal culture was positive for B. pertussis. Two age groups showed more susceptibility to B. pertussis, children under one year of age (70%) and of more than five years of age (20%). The disease was of more severity among infants younger than two months of age (apnea, choking spells, etc.). Most infants needed to be admitted to the hospital. All patients received therapy with erythromycin, salbutamol (80%) and general supportive medical care. No deaths or other medical sequelae were observed.
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