New hypoxanthine nucleosides with RNA antiviral activity
Related Experiment Videos
1Department of Chemistry, University of Iowa, Iowa City 52242.
Antiviral Research
|August 1, 1992
Abstract:
A series of novel C-2 functionalized hypoxanthine and purine ribonucleosides have been synthesized and evaluated against exotic RNA viruses of the family or genus alpha, arena, flavi, and rhabdo. Both specific and broad-spectrum antiviral activities were discovered but only with hypoxanthine nucleosides.