Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

A simple method to test condoms for penetration by viruses.

C D Lytle1, L B Routson, W H Cyr

  • 1Division of Life Sciences, Food and Drug Administration, Rockville, Maryland 20857.

Applied and Environmental Microbiology
|September 1, 1992
PubMed
Summary

A new, affordable method effectively tests virus penetration through condoms using bacteriophage and relevant pressure. This simple technique detects even minimal fluid leakage, ensuring condom safety.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

A double pass spectrometer for the far infrared.

Applied optics·2010
Same author

Electrostimulators for acupuncture: safety issues.

Journal of alternative and complementary medicine (New York, N.Y.)·2000
Same author

Viral impermeability of hypoallergenic, low protein, guayule latex films.

Journal of biomedical materials research·1999
Same author

Virus passage through track-etch membranes modified by salinity and a nonionic surfactant.

Applied and environmental microbiology·1999
Same author

Implications of laboratory tests of condom integrity.

Sexually transmitted diseases·1999
Same author

Evaluation of endoscope sheaths as viral barriers.

The Laryngoscope·1999

Area of Science:

  • Virology
  • Materials Science
  • Public Health

Background:

  • Condom integrity is crucial for preventing sexually transmitted infections.
  • Accurate and accessible testing methods for condom efficacy are needed.
  • Existing methods may be complex or costly.

Purpose of the Study:

  • To describe a simple, inexpensive method for testing virus penetration through condoms.
  • To validate the method using a specific bacteriophage and physiological pressure.

Main Methods:

  • Utilized the bacteriophage phi X174 as a model virus for penetration testing.
  • Applied physiologically relevant pressure to simulate real-world conditions.
  • Developed a detection system for minimal fluid volumes (≤0.1 microliters).

Related Experiment Videos

Main Results:

  • The described method successfully detected virus penetration through condoms.
  • The technique is sensitive enough to identify small leakage volumes.
  • Evaluated both latex and natural-membrane condoms using this approach.

Conclusions:

  • A simple and cost-effective method for assessing condom virus penetration has been established.
  • This technique can enhance the quality control and safety assessment of condoms.
  • Further application of this method can contribute to public health by ensuring reliable barrier protection.