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Assessment of anti-HIV activity of some benzimidazolylthiazoles
E A Badawey1, A A Hazzaa, S M Rida
1Department of Pharmaceutical Chemistry, Faculty of Pharmacy, University of Alexandria, A.R. Egypt.
Archiv Der Pharmazie
|September 1, 1992
Abstract:
Benzimidazolylthiazoles 2 were synthesized by condensing 1H-benzimidazole-2-acetonitrile (1) with sulphur and isothiocyanates. The syntheses of the Schiff bases 3, thioureas 4, and thiazolopyrimido[1,6-a]benzimidazoles 5 and 6 are also described. Seven compounds were evaluated in vitro against human HIV, however, no significant activity was observed with any of these compounds.