Primary squamous cell carcinoma of the breast

A patient with pure primary squamous cell carcinoma (SCC) of the breast is reported. The patient was a 72 year old female who presented with a 4 month history of an enlarging left breast mass. Surgery involved a radical mastectomy and this was followed by post-operative radiotherapy and chemotherapy. The patient died of extensive metastatic disease some four months after surgery. The various characteristics of SCC of the breast are briefly discussed. A sub-group of SCC of the breast is identified among reported cases in which the clinical course is characterised by a very rapid growth, extremely aggressive behaviour and early metastasis.