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Cardiac involvement in systemic sclerosis.

A Anvari1, W Graninger, B Schneider

  • 1Department of Cardiology, University of Vienna, Austria.

Arthritis and Rheumatism
|November 1, 1992
PubMed
Summary
This summary is machine-generated.

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Systemic sclerosis (SSc) patients often have cardiac abnormalities, even without symptoms. Advanced cardiac evaluations reveal high rates of arrhythmias and reduced ejection fraction in these individuals.

Area of Science:

  • Cardiology
  • Rheumatology
  • Internal Medicine

Background:

  • Systemic sclerosis (SSc) is a multisystem autoimmune disease.
  • Cardiac involvement is a significant cause of morbidity and mortality in SSc.
  • Subclinical cardiac dysfunction may precede overt symptoms.

Purpose of the Study:

  • To evaluate the prevalence and spectrum of cardiac abnormalities in SSc patients.
  • To investigate cardiac involvement in SSc patients lacking apparent cardiac symptoms.

Main Methods:

  • 18 SSc patients underwent comprehensive cardiac assessment.
  • Methods included surface and ambulatory electrocardiography, radionuclide ventriculography, myocardial scintigraphy, and echocardiography.

Main Results:

Related Experiment Videos

  • High incidence of arrhythmias: ventricular tachycardia (1), nonsustained ventricular tachycardia (5), supraventricular tachycardia (6).
  • Reduced ejection fraction observed in 2 (left) and 8 (right) patients.
  • Stress-induced reversible myocardial perfusion abnormalities were detected in 6 patients.

Conclusions:

  • Cardiac abnormalities are frequent in SSc patients, even in the absence of clinical symptoms.
  • Early detection of subclinical cardiac involvement is crucial for managing SSc patients.