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Ribonucleic acid in "transformation" of lymphoid cells

J A MANNICK, R H EGDAHL

    Science (New York, N.Y.)
    |September 21, 1962
    PubMed

    When incubated with "reactive" ribonucleic acid extracted from lymph nodes of rabbits immunized by skin homografts, "neutral" lymph node cells from nongrafted rabbits were apparently altered to a state of transpiantation immunity, as manifested by a positive skin reaction upon injection of these cells into the donor of the skin homografts.

    Keywords:
    LYMPH NODES/physiologyLYMPHOID TISSUE/physiologyRIBONUCLEIC ACID/pharmacologySKIN/physiology

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