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Biosensor for Detection of Antibiotic Resistant Staphylococcus Bacteria
14:04

Biosensor for Detection of Antibiotic Resistant Staphylococcus Bacteria

Published on: May 8, 2013

Yearly incidence of penicillin-resistant staphylococci in man since 1942

E MUNCH-PETERSEN, C BOUNDY

    Bulletin of the World Health Organization
    |January 1, 1962
    PubMed

    Insights

    Penicillin-resistant staphylococci carriage increased in humans from 1942-1959, particularly in those with clinical signs. This study analyzed medical literature to track resistance trends in different patient groups.

    Area of Science:

    • Microbiology
    • Infectious Diseases
    • Medical Literature Analysis

    Background:

    • Staphylococcal infections pose a significant public health challenge.
    • The emergence of antibiotic resistance, particularly penicillin resistance in Staphylococcus strains, has been a growing concern since the widespread use of penicillin.
    • Understanding the epidemiological trends of resistant staphylococci is crucial for effective treatment and prevention strategies.

    Purpose of the Study:

    • To analyze the year-by-year changes in the incidence of penicillin-resistant, coagulase-positive, or haemolytic staphylococci carriage or infection in humans.
    • To identify trends in resistant staphylococci across different population groups: hospitalized patients, outpatients with clinical signs, and individuals not receiving medical care.

    Main Methods:

    • Systematic analysis of 248 contributions to the medical literature.
    • Categorization of data based on patient population: hospital inpatients, outpatients with clinical signs, and the general population without current medical care.
    • Longitudinal data analysis from 1942 to 1959 to track incidence changes.

    Main Results:

    • A steady increase in penicillin-resistant staphylococci was observed in hospitalized individuals from 1942 to 1955, followed by a slight decrease until 1959.
    • Consistent increases in resistant strains were noted in outpatients with clinical signs and in the general population from 1942 to 1959.
    • The rate of increase in resistant strains was more pronounced among patients presenting with clinical signs.

    Conclusions:

    • The study highlights a significant rise in penicillin-resistant staphylococci across various human populations over the analyzed period.
    • Potential factors influencing resistance, such as penicillin ingestion with food and its presence in food sources, warrant further investigation.
    • Standardized methodologies for sampling, staphylococci testing, and resistance determination are essential for accurate epidemiological surveillance.
    Keywords:
    PENICILLIN/pharmacologySTAPHYLOCOCCUS/pharmacology

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