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Updated: Aug 9, 2026
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Basophil Activation Test for Investigation of IgE-Mediated Mechanisms in Drug Hypersensitivity
Published on: September 16, 2011
[Detection of IgG receptor subtype on basophils using two-color FCM]
1Second Department of Internal Medicine, Okayama University Medical School.
Nihon Rinsho. Japanese Journal of Clinical Medicine
|October 1, 1992
Abstract:
It was extremely difficult to phenotype basophils because they are most sparse among blood leukocytes. We developed a new method which identified basophils on the basis of negative reactivity with mixed monoclonal antibodies (CD2, CD14, CD16, CD19). Using this method we could detect Fc gamma R II (CDw32) but not Fc gamma R I (CD64) on basophil surface. The method seems useful for the study of clinical allergy and also of the biology of basophil.
