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[Six cases of primary pulmonary cryptococcosis]
Nihon Kyobu Shikkan Gakkai Zasshi
|September 1, 1992
Summary
Diagnosing and treating asymptomatic pulmonary cryptococcosis can be achieved non-surgically. Transbronchial biopsy and oral antifungal agents like fluconazole offer effective treatment for this fungal lung infection.
Area of Science:
- Pulmonology
- Infectious Diseases
- Radiology
Context:
- Asymptomatic primary pulmonary cryptococcosis is often detected incidentally through routine screenings.
- Chest X-rays may reveal solitary or multiple pulmonary nodules.
Purpose:
- To report on the diagnosis and treatment of six patients with asymptomatic primary pulmonary cryptococcosis.
- To evaluate the efficacy of non-surgical diagnostic and treatment methods.
Summary:
- Six patients with asymptomatic pulmonary cryptococcosis were diagnosed via chest X-ray screening.
- Transbronchial biopsy with bronchofiberscopy enabled histological diagnosis in 5 patients.
- Oral antifungal agents (flucytosine and/or fluconazole) led to significant improvement in chest X-ray findings.
Impact:
- Transbronchial biopsy and oral antifungal therapy are effective alternatives to surgical resection for primary pulmonary cryptococcosis.
- This approach facilitates accurate diagnosis and successful management of fungal lung infections.