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[Prokinetic drugs]
1Gastroenterologiska sekt, Medicinkliniken, Karolinska Sjukhuset, Stockholm.
Abstract:
Prokinetic drugs--preparations that stimulate gastro-intestinal motility--constitute a relatively new concept in medical therapy, chiefly represented by the products cisapride and metoclopramide. This review consists in an account of the physiological regulation of motility in the upper gastro-intestinal tract where prokinetic drugs are considered to exert their most significant effect, and the therapeutic effects demonstrable in treatment with these drugs.