Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Abnormal upper esophageal sphincter function in achalasia.

R S Dudnick1, J A Castell, D O Castell

  • 1Division of Gastroenterology and Hepatology, Jefferson Medical College, Philadelphia, Pennsylvania.

The American Journal of Gastroenterology
|December 1, 1992
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Viscous impedance is an important indicator of abnormal esophageal motility.

Neurogastroenterology and motility·2013
Same author

Swallowing activity assessed by ambulatory impedance-pH monitoring predicts awake and asleep periods at night.

Digestive diseases and sciences·2012
Same author

Twice-daily proton pump inhibitor therapy does not decrease the frequency of reflux episodes during nocturnal recumbency in patients with refractory GERD: analysis of 200 patients using multichannel intraluminal impedance-pH testing.

Diseases of the esophagus : official journal of the International Society for Diseases of the Esophagus·2012
Same author

Extraesophageal gastroesophageal reflux disease (GERD) symptoms are not more frequently associated with proximal esophageal reflux than typical GERD symptoms.

Diseases of the esophagus : official journal of the International Society for Diseases of the Esophagus·2012
Same author

Pneumatic dilation for achalasia--the way forward: authors' reply.

Alimentary pharmacology & therapeutics·2011
Same author

Review article: an analysis of the efficacy, perforation rates and methods used in pneumatic dilation for achalasia.

Alimentary pharmacology & therapeutics·2011

Achalasia patients show increased upper esophageal sphincter (UES) pressure and altered UES relaxation and pharyngeal contraction timing during swallowing, revealed by new manometry technology.

Area of Science:

  • Gastroenterology
  • Physiology

Background:

  • Achalasia is a motility disorder affecting the esophagus.
  • Pharyngeal and upper esophageal sphincter (UES) function in achalasia is not fully understood.

Purpose of the Study:

  • To investigate pharyngeal and UES manometry findings in achalasia patients.
  • To compare these findings with healthy controls using novel technology.

Main Methods:

  • Utilized new solid-state computerized manometry technology.
  • Evaluated 19 patients diagnosed with achalasia.
  • Compared results with 14 healthy control subjects.

Main Results:

  • Identified increased residual pressure in the UES as a key finding in achalasia.

Related Experiment Videos

  • Observed reduced duration of UES relaxation during swallowing in achalasia patients.
  • Noted a faster onset of pharyngeal contraction post-UES relaxation in achalasia.

    • Conclusions:

    • New manometry techniques reveal distinct pharyngeal and UES abnormalities in achalasia.
    • Findings contribute to understanding the pathophysiology of achalasia.
    • Results may inform diagnostic and therapeutic strategies for achalasia.