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Algorithms for a location database
N E Morton1, A Collins, S Lawrence
1CRC Research Group in Genetic Epidemiology, University of Southampton, U.K.
Annals of Human Genetics
|July 1, 1992
Abstract:
The algorithms that drive the ldb location database are described. The program captures data on genetic and physical maps and combines information from different sources into a summary map. To assure portability it was developed in Fortran on a SUN SPARCStation under Unix. The algorithms, which combine rule-based seriation with a minimum deviance bootstrap, allow investigators and chromosome committees to produce a composite location in Mb that integrates partial maps. The program and manual are now available from the authors.