Related Experiment Videos
Device-supported myocardial revascularization: safe help for sick hearts.
1Department of Thoracic and Cardiovascular Surgery, University of Texas Medical School, Houston 77030.
The Annals of Thoracic Surgery
|December 1, 1992
Summary
This study demonstrates that using ventricular assist devices during aortocoronary bypass surgery improves cardiac function in severely ill patients. This technique offers a safer alternative for complex cardiac revascularization procedures.
Area of Science:
- Cardiovascular Surgery
- Medical Technology
- Critical Care Medicine
Background:
- Aortocoronary bypass surgery has advanced, but efficacy is limited in severely ill patients.
- Intraoperative hemodynamic support and ventricular decompression are crucial for high-risk cardiac procedures.
Purpose of the Study:
- To evaluate the safety and efficacy of aortocoronary bypass using ventricular assist devices (VADs) in severely ill patients.
- To assess the impact of VAD support on cardiac function and outcomes in complex revascularization.
Main Methods:
- Forty-three severely ill patients underwent aortocoronary bypass with VAD support (Nimbus Hemopumps or Bio-Medicus centrifugal VADs).
- Operations were performed on beating hearts without cardioplegia or cardiopulmonary bypass, utilizing the patient's lungs as the oxygenator.
- Average VAD support duration was 112 minutes, with an average of 3.7 bypass grafts constructed per patient.
Main Results:
- Two patients (4.6%) died postoperatively; one from low cardiac output and another from a neurologic deficit.
- All surviving patients showed improved cardiac function in early and late follow-up periods (average 8.9 months).
- Preoperative ejection fractions averaged 0.22 in 34 patients, with 6 experiencing cardiogenic shock.
Conclusions:
- Ventricular assist devices provide effective intraoperative hemodynamic support and ventricular decompression during aortocoronary bypass in high-risk patients.
- This approach facilitates successful myocardial revascularization on beating hearts, leading to improved cardiac function post-surgery.
- The technique demonstrates a low mortality rate and significant functional recovery in a severely ill patient cohort.