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Primary Culture of Adult Rat Heart Myocytes
11:44

Primary Culture of Adult Rat Heart Myocytes

Published on: June 16, 2009

Modulation of transient type K channel cloned from rat heart

H Okada1, K Ishii, K Nunoki

  • 1Department of Pharmacology, Tohoku University School of Medicine, Sendai, Japan.

Biochemical and Biophysical Research Communications
|November 30, 1992
PubMed

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G-Protein Gated Ion Channels

GPCRs are primarily responsible for our sense of smell, taste, and vision.  The binding of a sensory stimulus activates GPCR to stimulate effector proteins, many of which are ion channels in the sensory organs. GPCRs modulate the opening and closing of the target ion channels either directly by binding them, or by releasing second messengers that activate these channels. As ions move across the membrane, the membrane potential is altered, which induces an appropriate response.
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