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Analysis of Global RNA Synthesis at the Single Cell Level following Hypoxia
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Analysis of Global RNA Synthesis at the Single Cell Level following Hypoxia

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Analysis of the effect of aging on the response to hypoxia by cDNA microarray

Hyungsoo Kim1, Dong-Ki Lee, Ji-Woong Choi

  • 1Department of Biochemistry and Molecular Biology, Cancer Research Institute, Seoul National University College of Medicine, 28 Yongon-dong, Chongro-gu, Seoul 110-799, South Korea.

Mechanisms of Ageing and Development
|September 23, 2003
PubMed

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DNA Microarrays02:34

DNA Microarrays

Microarrays are high-throughput and relatively inexpensive assays that can be automated to analyze large quantities of data at a time. They are used in genome-wide studies to compare gene or protein expression under two varied conditions, such as healthy and diseased states. Microarrays consist of glass or silica slides on which probe molecules are covalently attached through surface functionalization. Most commonly, the slides are prepared through the chemisorption of silanes to silica...