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Published on: March 29, 2022
Epidemiology of refractive errors and presbyopia
1Age Concern Institute of Gerontology, King's College London, University of London, London, United Kingdom.
Insights
This study examines epidemiological factors influencing refractive errors, highlighting prematurity, genetics, and age-related changes like increased anisometropia in presbyopes. It also explores myopia prevention and presbyopia links to accommodation.
Area of Science:
- Ophthalmology
- Epidemiology
- Genetics
Background:
- Existing epidemiological studies on refractive errors face limitations due to technical and statistical challenges.
- Early ocular parameters, such as prematurity, may influence refractive development.
- Familial and genetic factors play a role in refractive error progression.
Purpose of the Study:
- To comprehensively review the epidemiological aspects of refraction.
- To investigate age-specific influences on refractive errors, separating infants/toddlers from schoolchildren/teenagers.
- To examine the relationship between refractive errors, ocular pathologies, and potential prevention strategies for myopia and presbyopia.
Main Methods:
- Analysis of existing literature on refractive error epidemiology.
- Stratification of age groups (infants/toddlers, schoolchildren/teenagers, presbyopes).
- Consideration of demographic factors including sex and geographical distribution.
Main Results:
- Prematurity identified as a potential early influence on refraction.
- Anisometropia significantly increases among presbyopes, a novel finding.
- Refractive errors are linked to ocular pathologies; early myopia prevention strategies are discussed.
Conclusions:
- Refractive error epidemiology is complex, influenced by genetics, environment, and age.
- Anisometropia progression in presbyopia warrants further investigation.
- Understanding these factors is crucial for developing effective myopia and presbyopia management strategies.
Abstract:
Limitations in existing studies of the epidemiological aspects of refraction are attributed to both technical and statistical procedures. Early influences of ocular parameters on refraction are identified accordingly as prematurity and may or may not be involved. Attention is paid to familial and genetic influences, and infants and toddlers are examined as a group separate from schoolchildren and teenagers, who are likely to have experienced significant periods of near work. The effects of sex and geographical distribution are considered both for younger and older age ranges. Special attention is paid to anisometropia, which is shown-apparently for the first time-to increase appreciably among presbyopes. The connection between refractive errors and ocular pathologies is reviewed, and possible means of preventing early onset myopia are examined. Presbyopia is addressed with reference to its geographical distribution and hypothetical links to accommodation insufficiency.
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