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Related Experiment Video

Updated: Jul 29, 2026

Isolation of Human Lymphatic Endothelial Cells by Multi-parameter Fluorescence-activated Cell Sorting

Isolation of Human Lymphatic Endothelial Cells by Multi-parameter Fluorescence-activated Cell Sorting

Published on: May 1, 2015

Lymphoedema: an underestimated health problem.

C J Moffatt¹, P J Franks, D C Doherty

¹Centre for Research and Implementation of Clinical Practice, Faculty of Health & Human Sciences, Thames Valley University, 32-28 Uxbridge Road, London W5 2BS, UK. christine.moffatt@tvu.ac.uk

QJM : Monthly Journal of the Association of Physicians

|September 23, 2003

Summary

Chronic oedema affects many in the UK, with low recognition and treatment rates. This condition significantly impacts patients' quality of life and health resource use.

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Area of Science:

Medical research
Epidemiology
Public health

Background:

Chronic oedema (lymphoedema) is a significant cause of morbidity.
Its epidemiology and impact on patients and health services are poorly understood.

Purpose of the Study:

To determine the prevalence of chronic oedema in the community.
To assess its impact on healthcare resource utilization, employment, and quality of life.

Main Methods:

A questionnaire-based survey was conducted.
Health professionals in various services across South West London Community Trust provided data.
A subset of identified patients was interviewed.

Main Results:

A prevalence of 1.33/1000 was found, increasing with age and higher in women.
Only 64% of patients received treatment, despite specialist clinics.
Oedema caused significant work absence (80%), affected employment (9%), and reduced quality of life (50% experienced pain).
Acute infections led to hospital admissions and substantial costs.

Conclusions:

Chronic oedema is a widespread issue in the UK, affecting at least 100,000 individuals.
Non-cancer-related lymphoedema is more prevalent than often perceived.
Current treatment resources, often cancer-focused, lead to care inequalities.