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Related Experiment Videos

Heart rate variability in heart failure.

Agata Musialik-Łydka1, Beata Sredniawa, Stanisław Pasyk

  • 1Department of Cardiology, Silesian Medical Academy, Silesian Centre for Heart Diseases, Zabrze, Poland.

Kardiologia Polska
|September 23, 2003
PubMed
Summary
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Heart rate variability (HRV) is significantly reduced in patients with heart failure (CHF). Lower HRV indicates increased risk, particularly in those with diabetes, hypertension, or ventricular tachycardia.

Area of Science:

  • Cardiology
  • Autonomic Nervous System Research
  • Medical Diagnostics

Background:

  • Heart rate variability (HRV) reflects autonomic nervous system function and its impact on the sinus node.
  • HRV analysis is increasingly used in heart failure (CHF) patients to predict cardiac death risk.

Purpose of the Study:

  • To analyze HRV in CHF patients with reduced left ventricular ejection fraction (EF).
  • To correlate HRV parameters with EF, NYHA functional class, and other clinical factors.

Main Methods:

  • 105 CHF patients (NYHA class II-IV, EF <40%) and 30 healthy controls underwent 24-hour Holter ECG for HRV analysis.
  • Patients included ischaemic and dilated cardiomyopathy; controls were age- and gender-matched.

Main Results:

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  • CHF patients exhibited significantly lower HRV than controls.
  • Lower HRV (SDNN, SDANN) correlated with higher NYHA class, lower EF, and presence of ventricular tachycardia (VT).
  • Diabetes and hypertension were associated with reduced HRV (SDNN, rMSSD).

Conclusions:

  • HRV is depressed in CHF patients compared to healthy individuals.
  • Advanced NYHA class, lower EF, diabetes, hypertension, and VT further decrease HRV in CHF patients.